Last night UR4 was released for System Center 2019.
This includes patches for SCOM, SCSM, SCDPM and SCVMM.
These updates add supportability for Windows 2022 and 11 (on guest/agent side), .Net Framework 4.8, some security fixes, some bug fixes and some UI improvements.
See the article by the Product Group here:
System Center Update Rollup 4 – Microsoft Tech Community
Enjoy!